"By the start of the Lewis & Clark Expedition in 1803, American Indian tribes on the East Coast had nearly 200 years of interaction with the new immigrants to our lands. By 1790, the original 13 states were created: Connecticut, Delaware, Georgia, Maryland, Massachusetts, New Hampshire, New Jersey, New York, North Carolina, Pennsylvania, Rhode Island, South Carolina and Virginia. Shortly thereafter, Kentucky, Tennessee and Vermont became states. And by 1803, at the start of Lewis & Clark's journey, Ohio had become the 17th state in the new union.
"The push westward was well underway. By 1830, just 24 years after the Lewis & Clark Expedition, the newly passed Indian Removal Act forced many eastern tribes across the Mississippi River into Indian Territory, what is now present day Oklahoma. And in 1843, the Oregon Trail opened up the West from St. Louis all the way to the Pacific Ocean and California for settlement.
"Less than 50 years after Lewis & Clark mapped our homelands - in less than one lifetime - the landscape of Indian Country had changed forever."
A Guide to Visiting the Lands of Many Nations
Circle of Tribal Advisers of the Lewis & Clark Bicentennial